After a brain injury, raised temperaturemay be due to a regulated readjustment in thehypothalamic ‘set-point’ in response to inflammation.The purpose of this report is to mention possibleimplications related to temperature and homeostasisof morphine treatment in a patient with braininjury.During the month previous to her hospitalizationin our city she was treated for fever with paracetamoland metamizol without results. After 31 days withsimilar results, we changed to morphine IV consideringthe possibility of treating pain and fever. Thisoption was successful and afterwards we changed tofentanyl patches, keeping fever absent. After 100 daysof hospitalization, the patient was discharged to herhome.
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