The use of hydroquinone is forbidden as it is potentially carcinogenic and skin and respiratory irritant, nevertheless, it is still the most conventional and widely used in skin- lightening creams. In this study, thirty samples of Skin-lightening creams, local and imported, were analyzed for total hydroquinone by using high-performance liquid chromatography (HPLC). The concentration of hydroquinone ranged from 0.00% to 5.75 % and from 0.00% to 3.21% for local and imported creams, respectively. However, Fair and Lovely's cream ranged from 0.47% to 4.76% respectively. The use of such creams may lead to health hazards. Therefore, it is recommended that all skin-lightening creams should be checked for hydroquinone levels before marketing.