Introduction: Evaluating childhood asthma programs is an important step for their successful implementation. However, no specific guidelines or method of evaluation are recommended as it is evident in the diversity of methodologies and measures used in previous evaluation studies. The purpose of this paper was to conduct a review to provide guidelines for evaluating childhood asthma programs. Methods: A random sample of 39 evaluation studies was reviewed and lessons learned were documented. Results: Programs appear to be effective in reducing morbidity attributed to asthma hence are an important part of asthma management. The included table is a summary of main lessons learned in evaluating childhood asthma programs. Conclusion: Evaluating asthma programs is an important step for their successful implementation. Lessons learned from the literature can provide valuable guidelines for international researchers to conduct successful evaluations.