An insecticide is an agent used against insects, ticks, mites and other animals affecting human welfare. Exposure to Insecticides is one of the most important occupational risks among staff worker in Military camp, veterinary medicine, industry and household as well as schools and hospitals. This study Aimed to improve nursing staff knowledge regarding adverse health effects of chemical insecticides exposure in a military field. Setting: The study was conducted in one of the Main Military Hospital. Research design: was used a quasi-experimental research design to conduct this study. Subject: all nursing staff who work in a Military Hospital (n=55) who accept to participate in the research study. Results: A significant improvement in the Nurses’ Total knowledge score was found in post-test as compared to that in pre-test. All nurses obtained a satisfactory level of knowledge after the 1st & 2nd post-tests; all of them evaluate the program in relation to trainees' expectations as “excellent”.