Organizations need to present new and unique services with low price, to survive in today’s competitive and complex environment; however it should has a desired benefit for them. Many companies have to seek some solutions for predicting and reducing their costs, to ensure that their products and services with current quality and price will be successful in the market. Given that many decisions in business and economic institutions have not been organized, and considering the fact that one of the important features of decision support system is solving unstructured problems, so this system can have an appropriate performance in these affairs. Hence, this paper at first attempts to consider the concept of decision support system and its capabilities in the organizations, and then examine the impact of implementation this system on predicting and reducing costs of organizations. According to the discussions it can be concluded that implementation of decision support system has a positive impact on predicting and reducing operational, personnel, and staff costs, and also those costs which are resulted from irrelative and inaccurate information. At the end, according to the obtained results, a series of suggestions are presented to improve the process of implementing this system in the organizations