The aim of the article was to evaluate the treatment potential for focaltherapies of prostate cancer (PCa). A literature research was performed toevaluate efficiency of the minimally invasive methods of PCa treatment.The two treatment methods evaluated were high-intensity focusedultrasonography (HIFU) and cryoablation. There are few studies withsufficient long-term follow-up and follow-up criteria are very diverse. Theincreasing number of cryoablation and HIFU treatments in the last 10 yearsconfirms the considerable demand for minimally invasive treatment forlocalized PCa. Focal ablation of PCa is an interesting treatment option forlow-risk PCa, but there are not many opportunities for this treatment and thepatient experience is often negative.