The major purpose of the study was to examine the entrepreneurial skills required bybusiness related graduates for successful operation of a business enterprise in EnuguCommercial Centre and Environs. Specifically, the study examined the management skills,marketing skills, and accounting skills required by business related graduates for successfuloperation of a business enterprise. Three research questions were answered. Relatedliterature and some empirical studies were reviewed. The study employed a survey researchdesign and the population consisted of 300 respondents (managers). A modified 4 – pointLikert rating scale made up of 29 structure questionnaire items was used in generating datafor the study, while the instrument was face validated by some experts. Data collectionwere analyzed using the statistical mean (x) and standard deviation. The finding revealed 9management skills, 9 marketing skills and 8 accounting skills required by business relatedgraduates for successful operation of a business enterprise. The capital based of themanagers are not source of significant difference regarding the management, marketingand accounting skills required for successful operation of a business enterprise. It wasrecommended among others that the Business related curriculum should be reviewed with aview of dropping old courses that are no longer relevant, while new courses which haverelevancy with the demands of the present day society be introduced to ensure theproduction of Business graduates that can face the challenges emanating from employmentopportunities and being able to establish, manage and operate business enterprisers of theirown.